A specific pattern of brain activity could be a sign of early Alzheimer's disease U.S researchers report.
They noted that as new treatments for Alzheimer's become available ,spotting the disease early will become critical.A team at Duke University Medical Center in Durham,N.C.,used functional magnetic resonance imaging (FMRI) to study the brains of 13 patients with mild Alzheimer's disease,34 patients with mild cognitive impairment,and 28 healthy people (averaging about 73 years of age) as they did a memory task.
Participants with mild Alzheimer's and mild cognitive impairment showed impaired activity in the medial temporal lobe (MTL),an area of the brain associated with episodic memory that normally turns on during a memory task.previous research had found that structural changes in the MTL are among the earliest known brain changes in people with Alzheimer's disease.More surprisingly,the researchers found impaired deactivation in the posteromedial cortex (PMC),a brain area involved in personal memory that's usually suppressed during a memory task.
(Source: HealthDay News)
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